Last Updated on Friday, 26 March 2010 06:27
Written by Josh White
Saturday, 27 February 2010 00:00

Scientists separately in the U.S. and the U.K. have been working on developing an artificial liver. The artificial liver works outside the body in a way similar to kidney dialysis. The idea is to create a device that would buy time for a patient with acute liver failure where the liver has the potential to regenerate. Blood would be taken from the patient directly into the bioartificial liver, allowing their own liver a rest from processing toxins. This could allow the patient's liver to heal itself. The treatment would take a number of weeks or months before the liver was repaired.
It could also be used as a bridge to transplantation where the patient has chronic liver failure due to hepatitis, cirrhosis or other irreversible damage, and would buy valuable time before transplantation. It will provide some of the lost functions.
HepaMate™ made by Hepalife will be undergoing a new pivotal Phase III clinical trial in the United States in 2010. It follows a clinical Phase I and pivotal Phase II/III studies involving more than 200 patients. which revealed a statistically significant survival advantage for patients with fulminant and subfulminant hepatic failure when treated with HepaMate compared to controls receiving standard medical care alone.
Read more: Artificial Livers
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