The intervertebral disc is a cartilage that cushions the stress forces on the spine and enables the normal rotation of the spine. With advancing age, there is progressive loss of the proteoglycan material that gives the disc its properties, and a consequent increased risk of damage to the spine. This process, termed degenerative disc disease, affects 20-25 per cent of the population.
Melbourne, VIC, 3000, Australia
Since MPC produce the proteoglycan materials found in discs, Mesoblast envisages that the injection of MPC into a degenerated intervertebral disc will lead to replacement of the protoeglycan of cartilage. This approach, with its anticipated ease of application and lack of side-effects, should offer a relatively non-invasive and cost-effective therapy for patients with moderate or se ...
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The Medtronic Vertex Select system is designed for posterior fusions that require the skull to be stabilized to the neck.
When a patient has a serious spinal condition that requires the base of the skull (occiput) to be fused, or joined, to the neck (cervical-upper thoracic spine), this complex procedure must be performed from the back of the spine, also known as a posterior a ...
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230 Constitution Drive, Menlo Park, California, 94025, USA
Geron is developing first-in-class biopharmaceuticals for the treatment of cancer and chronic degenerative diseases, including spinal cord injury, heart failure and diabetes. The company is advancing an anti-cancer drug and a cancer vaccine that target the enzyme telomerase through multiple clinical trials. Geron is also the world leader in the development of human embryonic stem ce ...
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The CHARITÉ® Artificial Disc is made of cobalt chromium endplates coated with titanium calcium phosphate and an ultra-high molecular weight polyethylene sliding core. It's an alternative treatment option to spinal fusion which preserves some motion and avoids pain at the donor site.
Preclinical testing indicates that the unique mobile-core design incorporates a floating ce ...
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Medtronic’s fifth generation spinal fusion system. Designed to treat patients with degenerative disc disease, spinal stenosis, fracture, dislocation, failed previous fusions, tumors and, uniquely, adolescent idiopathic scoliosis. Extending the unmatched clinical history of more than twenty-five years and 500,000 patients represented by the CD HORIZON® product line, the CD HORIZON® S ...
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Bone Solutions have announced a completed pilot study showing that OsteoCrete™ may be the first bone void filler to be successfully used as a fusion-facilitator in a rabbit posterolateral lumbar spine model. OsteoCrete™ is already FDA-cleared as a bone void filler (BVF). The Company also announced that it intends to commence production of OsteoCrete™ early in the fourth quarter of t ...
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In August 2011 the U.S. FDA has approved the SImmetry™ Sacroiliac Joint Fusion System for sacroiliac joint fusion for conditions including sacroiliac joint disruptions and degenerative sacroiliitis. "We are very pleased that the FDA approved the updated indications for use for SImmetry. We believe performing a true, intra-articular arthrodesis of the SI joint provides the best path ...
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he AXLE™-PEEK Interspinous Fusion System consists of spinal implants that are FDA-cleared for the treatment of degenerative disk disease (DDD). The system expands on X-spine’s AXLE™ line of interspinous fusion devices by incorporating an insert manufactured from PEEK-OPTIMA® provided by Invibio Biomaterial Solutions. The AXLE-PEEK implants can be placed through a smaller incision an ...
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